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HRT News Archives:Estrogen therapy increases a women's heart risks - Preliminary results of a major long-term study suggest that hormone replacement therapy (HRT) -- which many postmenopausal women take to reduce heart risks -- may actually increase chances for stroke or heart attack - Reuters Health, April 5, 2000 Hormone Replacement Therapy Reduces Accuracy of Mammograms – A study published in Lancet looked at the mammograms of nearly 104,000 women with no history of breast cancer and found a decreased sensitivity in the test among those women on hormone replacement therapy. This means that the test was less accurate in detecting cancer in women on hormone replacement therapy (HRT). Mammograms were found to be 65 percent accurate in the HRT group compared to 77.3 percent in the group that did not use HRT. Among women 50 to 69 years old, the sensitivities were 64.3 percent and 79.8 percent respectively. Of women on HRT, those who were diagnosed with cancer during the study period were more likely to have test results that showed no cancer when in fact cancer was present. This group was compared to women not on HRT. There was also a greater risk of results suggesting cancer was present when it wasn't in women on HRT. Ivanhoe News, 3/24/2000 Hormones and uterine cancer - A combination of estrogen and progestin used to protect women against heart disease and other conditions after menopause nearly doubles the risk of breast cancer, researchers are reporting. Women have been taking the combination to reduce risk of endometrial cancer. The study compared women who used estrogen, the estrogen-progestin combination and those who used no hormone replacement therapy. They found the estrogen-progestin regimen increased breast cancer risk beyond that associated with estrogen alone. In an accompanying editorial, Dr. Walter Willett of the Harvard School of Public Health says reliance on post-menopausal drugs "has unfortunately led to neglect of diet and lifestyle as the primary means to achieve healthy aging. Now is an appropriate time to reassess this emphasis." Journal of the American Medical Association Accidental estrogen exposure can harm children - Estrogen creams often used by women to counter the symptoms of menopause, such as hot flashes can cause problems in children who come into contact with them accidentally. A report of three young boys who developed breasts after their mothers started using these creams. When their mothers stopped using the creams, all three boys returned to normal within several months, and their growth rate slowed down. In these cases, exposure to estrogen appeared to be indirect, and may have come from traces of the hormone on the hands of women spread to foods during food preparation - Pediatrics, April 2000.
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